- Fatigue and weakness
- Abnormal reflexes (absent or exaggerated)
- Visual disturbances (double vision and nystagmus [involuntary eye movement])
- Motor dysfunction, such as weakness, tremor, and uncoordinated movements
- Sensory disturbances, such as paresthesia, impaired deep sensation, and impaired vibratory and position sense
- Impaired speech (dysarthria)
- Urinary dysfunction, such as hesitancy, frequency, urgency, and retention
- Neurobehavioral syndromes, such as depression, cognitive impairment, and emotional lability
McCormick, M. (2010). Degenerative disorders: ALS and MS. Nursing Made Incredibly Easy, 8(3), 28-36.